Table 2:
Toxicity & Treatment
| Toxicity | N=73 (%) |
|---|---|
| CRS | 62 (85) |
| *Maximal grade | |
| 1 | 47 (64) |
| 2 | 8 (11) |
| 3 | 5 (7) |
| 4 | 2 (3) |
| Time from infusion (days), median (range) | 4 (2-5) |
| Duration (days), median (range) | 5 (4-9) |
| Treatment | 12 (13) |
| Tocilizumab | 5 (7) |
| Tocilizumab + steroids | 4 (6) |
| ICANS | 29 (40) |
| Maximal grade | |
| 1 | 9 (12) |
| 2 | 4 (6) |
| 3 | 12 (16) |
| 4 | 4 (6) |
| Time from infusion (days), median (range) | 7 (6-9) |
| Duration (days), median (range) | 4 (2-7) |
| Treatment | 29 (40) |
| Steroids | 6 (8) |
| Anti-epileptics | 7 (10) |
| Steroids + anti-epileptics | 16 (22) |
Abbreviations:
CRS – Cytokine Release Syndrome
ICANS - Immune Effector Cell-associated Neurotoxicity Syndrome