Table 3.
Protein expression patterns of PD-L1 in tumor and immune cells with 3 monoclonal antibodies (N = 59)
| PD-L1 antibody | Membranous staining (TC) | Cytoplasmic staining (Cyt) | Immuno cells staining (IC) | ||||
|---|---|---|---|---|---|---|---|
| Negative (< 1%) | Positive (1–50%) | Strong positive (> 50%) | Negative | Positive | Negative (< 1%) | Positive (> 1%) | |
| 22C3 | 46 (78%) | 12 (20.3) | 1 (1.7%) | 35 (59.3%) | 24 (40.7%) | – | – |
| 28-8 | 46 (78%) | 12 (20.3) | 1 (1.7%) | 35 (59.3%) | 24 (40.7%) | – | – |
| SP142 | – | – | – | – | – | 35 (59.3%) | 24 (40.7%) |
TC Tumor cell, Cyt Cytoplasma, IC Immune cell