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. 2022 Jul 15;164(10):2731–2740. doi: 10.1007/s00701-022-05277-9

Table 3.

Results from the multivariable logistic regression analysis including an interaction term

Variable OR (95% CI) p value
12-month mortality
Agea 1.05 (1.05–1.06)  < 0.001
Female 0.86 (0.71–1.04) 0.121
GCSa 0.81 (0.79–0.83)  < 0.01
Chronic comorbidity 2.14 (1.66–2.77)  < 0.001
Operative admission 0.82 (0.68–0.98) 0.032
Modified SAPS IIa, b 1.08 (1.07–1.09)  < 0.001
Admission yeara 0.98 (0.97–1.00) 0.106
Platelet count, × 109/La 1.00 (0.99–1.00) 0.783
Platelet transfusion 1.53 (0.99–2.38) 0.058
Platelet count, × 109/L*Platelet transfusion interaction term
   ≥ 100 * no transfusion Base
   < 100 * no transfusion 2.18 (1.60–2.97)  < 0.001
   < 100 * transfusion 0.97 (0.55–1.70) 0.912

No interaction term between platelet level ≥ 100 and platelet transfusion could be established due to the low number of patients receiving transfusion and strong correlation between no transfusion and normal platelet count

CI confidence interval, GCS Glasgow coma scale, OR odds ratio, SAPS simplified acute physiology score

aOR for one-unit increase in continuous variables

bSAPS II score excluding points for GCS, chronic disease, age, and admission type (operative vs non-operative)