Table 3.

Age-stratified findings per 1000 scans. Numbers in parentheses represent the 95% confidence interval. Findings derived from univariable restricted cubic spline meta-regression models

			Age in years
Finding	τ2	I2	1	5	10	20	30	40	50	60	70	80	Grade
Vascular
Aneurysm	0.0036	94%	0 (0–5)	0 (0–3)	0 (0–2)	0 (0–0.7)	0 (0–2)	0.9 (0–4)	4 (1–8)	6 (3–9)	5 (1–10)	3 (0–14)	Low
Cavernoma	0.001	80%	0.00001 (0–6)	0.1 (0–5)	0.4 (0–4)	2 (0.003–5)	3 (0.03–8)	3 (0.3–7)	2 (0.4–6)	3 (0.7–6)	5 (1–10)	7 (0.3–20)	Low
Other vascular	0.0008	71%	0 (0–7)	0.02 (0–5)	0.1 (0–4)	0.6 (0–3)	1 (0–6)	1 (0–6)	1 (0––4)	1 (0–4)	2 (0–6)	2 (0–13)	Very low
Any vascular	0.0037	94%	2 (0–17)	2 (0–14)	3 (0–11)	4 (0.4–10)	5 (0.3–15)	7 (2–15)	9 (4–17)	11 (6–19)	14 (5–26)	16 (1–43)	Very low
Neoplastic
Meningioma	0.0038	95%	0 (0–2)	0 (0–2)	0 (0–1)	0.1 (0–2)	1 (0–7)	3 (0.2–9)	5 (2–10)	8 (4–13)	12 (5–21)	17 (4–37)	Low
Pituitary	0.0005	69%	0 (0–2)	0 (0–2)	0 (0–2)	0.6 (0–2)	2 (0–5)	2 (0.2–5)	2 (0.3–4)	2 (0.5–4)	3 (0.6–7)	4 (0.03–13)	Low
Glioma	0.0001	40%	1 (0–5)	0.9 (0–4)	0.8 (0.0003–2)	0.6 (0–2)	0.3 (0–2)	0.06 (0–1)	0 (0–0.4)	0 (0–0.3)	0.05 (0–1)	0.2 (0–4)	Low
Other neoplastic	0.0009	81%	0 (0–3)	0 (0–3)	0.03 (0–2)	1 (0–4)	2 (0.007–7)	2 (0.02–5)	0.9 (0–3)	2 (0.2–4)	5 (1–10)	9 (1–23)	Very low
Any neoplastic	0.0033	94%	0.2 (0–10)	0.8 (0–9)	2 (0–8)	5 (1–11)	8 (2–18)	9 (3–18)	11 (5–18)	15 (9–22)	24 (13–37)	34 (12–66)	Very low
Chiari malformation	0.0017	85%	8 (0–29)	8 (0.3–23)	7 (1–16)	6 (1–13)	4 (0.07–12)	2 (0.002–8)	1 (0–6)	0.5 (0–3)	0.1 (0–4)	0 (0–8)	Low
Pineal cyst	0.0211	99%	11 (0–71)	13 (0–57)	15 (0.7–44)	19 (4–44)	12 (0–41)	1 (0–13)	0 (0–4)	0.6 (0–10)	22 (3–55)	72 (12–175)	Very low
Arachnoid cyst	0.0016	87%	19 (4–44)	16 (4–34)	12 (5–23)	7 (2–14)	4 (0–12)	3 (0.02–9)	4 (0.6–10)	7 (2–12)	10 (3–19)	14 (1–37)	Low