Fig. 1.

Timeline of events for the multisite RCT study conducted at SE and Pacific NW and VA Health Care Systems. Trials began in March 2016 at the SE site. Eight cohorts were conducted between March 2016 and February 2020 when the Pacific NW site was approved by the IRB to begin recruitment. In February 2020, recruitment for cohort one at the Pacific NW site coincided with completing cohort eight and enrolling cohort nine at the SE site. In March 2020, COVID-19 shutdowns occurred and study was converted to virtual format. In July 2021, interventions were completed at both sites. IRB, Institutional Review Boards; NW, Northwestern; RCT, randomized controlled trial; SE, Southeastern; VA, Veterans affairs.