Table 3.
Non-Hispanic White population
|
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---|---|---|---|---|---|---|
Steatosis | Lobular inflammation | Ballooning degeneration | Portal inflammation | Fibrosis | ||
|
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Steatosis | Adj. β | 0.16 | 0.07 | −0.07 | −0.11 | |
P-value | <0.001 | 0.018 | 0.001 | 0.011 | ||
Lobular inflammation | Adj. β | 0.49 | 0.11 | 0.41 | ||
P-value | <0.001 | <0.001 | <0.001 | |||
Ballooning degeneration | Adj. β | 0.12 | 0.65 | |||
P-value | <0.001 | <0.001 | ||||
Portal inflammation | Adj. β | 0.94 | ||||
P-value | <0.001 | |||||
Other racial/ethnic groups |
||||||
Steatosis | Adj. β | 0.13 | −0.07 | −0.08 | −0.13 | |
P-value | 0.005 | 0.192 | 0.036 | 0.05 | ||
Lobular inflammation | Adj. β | 0.42 | 0.11 | 0.46 | ||
P-value | <0.001 | 0.008 | <0.001 | |||
Ballooning degeneration | Adj. β | 0.14 | 0.70 | |||
P-value | <0.001 | <0.001 | ||||
Portal inflammation | Adj. β | 0.68 | ||||
P-value | <0.001 |
Multivariable linear regression models adjusting for age, gender, body mass index (kg/m2), T2DM, non-heavy alcohol intake, PNPLA3 rs738409, HSD17B13 rs72613567, TM6SF2 rs58542926, MBOAT7 rs641738. Race/ethnicity was further included in the multivariable analysis focusing on the other racial/ethnic groups cohort.