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. Author manuscript; available in PMC: 2023 Nov 1.
Published in final edited form as: Hepatology. 2022 Apr 21;76(5):1482–1494. doi: 10.1002/hep.32491

Table 3.

Covariate-adjusted* correlations between all histological lesions. Results based on multivariable linear regression. NH-White (n=1153) and other racial/ethnic groups (n=404) populations.

Non-Hispanic White population
Steatosis Lobular inflammation Ballooning degeneration Portal inflammation Fibrosis

Steatosis Adj. β 0.16 0.07 −0.07 −0.11
P-value <0.001 0.018 0.001 0.011
Lobular inflammation Adj. β 0.49 0.11 0.41
P-value <0.001 <0.001 <0.001
Ballooning degeneration Adj. β 0.12 0.65
P-value <0.001 <0.001
Portal inflammation Adj. β 0.94
P-value <0.001

Other racial/ethnic groups
Steatosis Adj. β 0.13 −0.07 −0.08 −0.13
P-value 0.005 0.192 0.036 0.05
Lobular inflammation Adj. β 0.42 0.11 0.46
P-value <0.001 0.008 <0.001
Ballooning degeneration Adj. β 0.14 0.70
P-value <0.001 <0.001
Portal inflammation Adj. β 0.68
P-value <0.001
*

Multivariable linear regression models adjusting for age, gender, body mass index (kg/m2), T2DM, non-heavy alcohol intake, PNPLA3 rs738409, HSD17B13 rs72613567, TM6SF2 rs58542926, MBOAT7 rs641738. Race/ethnicity was further included in the multivariable analysis focusing on the other racial/ethnic groups cohort.