Table 10.

Weight loss targets based on comorbidities[45]

Disease	Weight loss in %	Expected outcome
Type 2 diabetes mellitus	5-15	Reduction in HbA1c, reduction in drugs, reversal of diabetes
Metabolic syndrome	7-10	Prevention of diabetes
NAFLD	7-10	Reduction in intrahepatocyte fat and NASH resolution (64%-90%)[46]
PCOS	5-15	Ovulation, reduction in insulin resistance and hirsutism
Dyslipidemia	5-15	Reduction in triglyceride and LDL, rise in HDL
Hypertension	5-15	Lower blood pressure and decreased medications
Sleep apnea	7-11	Decrease in apnea and hypopnea index