Table 3.
Summary of DNA-bending angles induced by MBD2sc and MBD3sc binding
| DNA | MBD2sc |
MBD3sc |
||
|---|---|---|---|---|
| Bending angle (°) | N | Bending angle (°) | N | |
| Unmethylated | ||||
| CpG-free region | 49 ± 28 | 97 | 47 ± 26 | 168 |
| CpG-rich region | 77 ± 27 | 95 | 68 ± 28 | 119 |
| Methylated | ||||
| CpG-free region | 49 ± 30 | 99 | 36 ± 26 | 168 |
| CpG-rich region | 91 ± 27 | 131 | 82 ± 30 | 138 |
The values represent mean ± SD from 2 to 3 experiments for each data set. The significance values regarding the difference among the datasets are reported in Supplementary Figure 7.