Table 1.
Demographic characteristics, co-occurring disorders, and frequency of outcomes in study groups.
| Study group | |||
|---|---|---|---|
| Antidepressanta | Non-antidepressant 1b | Non-antidepressant 2c | |
| n = 500 | n = 573 | n = 593 | |
| Demographic characteristics | |||
| Age, median (IQR) y | 71 (60, 82) | 71 (58, 80) | 71 (59, 80) |
| Sex | |||
| Female, No. (%) | 284 (56.8) | 297 (51.8) | 316 (53.3) |
| Male, No. (%) | 216 (43.2) | 276 (48.2) | 277 (46.7) |
| Race | |||
| White, No. (%) | 390 (78.0) | 397 (69.3) | 413 (69.7) |
| African American, No. (%) | 45 (9.0) | 57 (10.0) | 54 (9.1) |
| Asian American or Pacific Islander, No. (%) | 9 (1.8) | 13 (2.3) | 22 (3.7) |
| Other or not recorded, No. (%) | 56 (11.2) | 106 (18.4) | 104 (17.5) |
| Ethnicity | |||
| Non-Hispanic, No. (%) | 413 (82.6) | 435 (75.9) | 460 (77.6) |
| Hispanic, No. (%) | 71 (14.2) | 109 (19.0) | 108 (18.2) |
| Other or not recorded, No. (%) | 16 (3.1) | 29 (5.0) | 25 (4.2) |
| Co-occurring disorders (ICD-10 code) | |||
| Neoplasms (C00-D49) | 46 (9.2) | 90 (15.7) | 81 (13.7) |
| Disorders of the blood and immune system (D50-D89) | 123 (24.6) | 164 (28.6) | 185 (31.2) |
| Diabetes (E10, E11) | 121 (24.2) | 131 (22.9) | 140 (23.6) |
| Obesity (E66) | 57 (11.4) | 68 (11.9) | 47 (7.9) |
| Diseases of the circulatory system (I00-I99) | 361 (72.2) | 418 (73.0) | 430 (72.51) |
| Diseases of the respiratory system (J00-J99) | 335 (67.0) | 404 (71.5) | 421 (71.0) |
| Mood and anxiety disorders (F30-F48) | 195 (39.0) | 79 (13.8) | 91 (15.4) |
| Other psychiatric disorders (F00-F29, F50-F99) | 130 (26.0) | 87 (15.2) | 114 (19.2) |
| Diseases of the nervous system (G00-G99) | 175 (35.0) | 153 (26.7) | 161 (19.2) |
| Observation time | |||
| Days under observation, median (IQR) | 7 (4, 15) | 7 (4, 15) | 7 (4, 16) |
| Outcomes | |||
| Intubation or death composite, No. (%) | 120 (24.0) | 119 (20.7) | 127 (21.4) |
| Death, No. (%) | 101 (20.2) | 87 (15.2) | 102 (17.2) |
| Intubation | 35 (7.0) | 50 (8.7) | 46 (7.8) |
IQR, interquartile range.
a
Patients prescribed one or more antidepressant medications on admission (see text and Table 2 for details).
b
Frequency matched to antidepressant group by age, sex, and race/ethnicity.
c
Frequency matched to antidepressant group by age, sex, race/ethnicity, and “comparative health.”