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. 2022 Sep 15;9:933532. doi: 10.3389/fcvm.2022.933532

TABLE 3.

Logistic regression analysis of the correlation between specific markers, risk factors and ADHF events.

Variables Univariate analysis
Multivariate analysis
OR(95% CI) P-value OR(95% CI) P-value
Male 1.49 (0.78–2.85) 0.229
Age 1.03 (1.01–1.06) 0.002 1.04 (1.01-1.06) 0.002
Hypertension 1.75 (0.95–3.23) 0.075
Diabetes 1.75 (0.82–3.71) 0.146
CHD 2.56 (1.33–4.93) 0.005 2.56 (0.62-10.64) 0.197
Target vessel
LAD 2.18 (1.11–4.28) 0.023 0.85 (0.19-3.88) 0.833
LCX 2.76 (1.08–7.05) 0.135
RCA 1.46 (0.61–3.50) 0.397
Single-vessel disease 1.15 (0.53–2.49) 0.722
Multi-vessel disease 3.54 (1.48–8.46) 0.005 1.47 (0.45-4.82) 0.528
CD4+ Tim-3+ high level 3.72 (1.96–7.06) <0.001 2.76 (1.34-5.65) 0.006
CD8+ Tim-3+ high level 3.35 (1.78–6.32) <0.001 2.58 (1.26-5.31) 0.010

CHD, Coronary heart disease; LAD, Left anterior descending branch; LCX, Left circumflex branch; RCA, Right coronary artery; CD4+Tim-3+ high level, The highest quartile (Q3–Q4) of Tim-3 expression on CD4+T cells; CD8+Tim-3+ high level, The highest quartile (Q3–Q4) of Tim-3 expression on CD8+T cells.