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. 2022 Sep 15;9:956188. doi: 10.3389/fmed.2022.956188

TABLE 3.

Comparison of intervention effects and MCID.

Outcome MCID High intensity laser therapy Vs. Placebo laser (plus exercise)

*Change scores #Clinical decision
VAS-pain 0.9 1.66 (1.48, 1.84) Very likely
WOMAC-pain 1.42 2.74 (2.41, 3.08) Very likely
WOMAC-stiffness 1.30 0.78 (0.52, 1.04) Very unlikely
WOMAC-function 7.65 8.37 (6.90, 9.85) Likely
WOMAC-total 10.37 10.87 (8.85, 12.88) Likely

MCID, minimal clinically important difference; VAS, visual analog scale; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index. *Values are weighted mean difference (95% confidence interval). #Likely to obtain an effect of the stated size when intervention is used. Very likely, The mean of change scores outweigh MCID, and the lower bound of the 95% CI is more than the MCID. Likely, The mean of change scores outweigh MCID, but the lower bound of the 95% CI is less than the MCID. Very unlikely, The mean of change scores below MCID, and the upper bound of the 95% CI is less than the MCID.