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. 2022 Sep 24;57:102491. doi: 10.1016/j.redox.2022.102491

Fig. 8.

Fig. 8

Suboptimal concentrations of vitamin C impact on mitochondrial complex III activity, ATP, and ROS levels in Gulo−/− mice liver. (A) Mitochondrial complex III activity measurements in MEE samples from female and male GL00, GL01, and GL40 mice groups (N = 6–11 females and males combined per group, ANOVA p-values < 0.0001). (B) ATP levels quantification in whole liver lysates of female and male GL00, GL01, and GL40 mice (N = 13–14 females and males combined per group, ANOVA p-values < 0.001). (C) ROS levels evaluation using whole liver lysates of female and male GL00, GL01, and GL40 (N = 16 females and males combined per group, ANOVA p-values < 0.0001). Bars in each histogram represent mean ± SEM. Significant differences are indicated using * (with a Tukey post ANOVA tests p-value < 0.05).