Table 1.
Data at enrolment | |||
---|---|---|---|
Age (years) | 65 ± 10 | ||
Males (n, %) | 61 | 86% | |
NYHA II (n, %) | 65 | 82% | |
NYHA III (n, %) | 14 | 18% | |
SBP (mmHg) | 115 ± 16 | ||
DBP (mmHg) | 73 ± 9 | ||
Heart rate (bpm) | 68 ± 11 | ||
BMI (kg/m2) | 26.9 ± 4.3 | ||
NT-proBNP (pg/ml) | 1,196 [648–2,891] | ||
Hemoglobin (g/dl) | 14.3 ± 1.6 | ||
Creatinine (mg/dl) | 1.20 ± 0.26 | ||
GFR (ml/min/1,73 m2) | 66 ± 17 | ||
Sodium (mmol/l) | 141 ± 3 | ||
Potassium (mmol/l) | 4.32 ± 0.42 | ||
Therapy | |||
ACE-I (n, %) | 53 | 75% | |
ARBs (n, %) | 16 | 23% | |
Beta blockers (n, %) | 70 | 99% | |
MRA (n, %) | 49 | 69% | |
Diuretic (n, %) | 57 | 80% | |
Ivabradine (n, %) | 9 | 13% | |
Digoxin (n, %) | 6 | 8% | |
Amiodarone (n, %) | 30 | 42% |
NYHA, New York Heart Association; SBP, systolic blood pressure; DBP, diastolic blood pressure; BMI, body mass index; NT-proBNP, amino terminal pro-B-type natriuretic peptide; GFR, glomerular filtration rate assessed by Modification of Diet in Renal Disease (MDRD) equation; ACE-I, angiotensin-converting-enzyme inhibitors; ARBs, angiotensin receptor blockers; MRA, mineralocorticoid receptor antagonists.