Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Sep 15;14:969381. doi: 10.3389/fnagi.2022.969381

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Muntsant and Giménez-Llort.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Salient behavioral alterations in 18-month-old female 3xTg-AD mice in the open field tests compared to NTg females with normal aging. Results are expressed as mean ± SEM. (A) OF: Open field test Horizontal activity: left, time course; and right, total distance; (B) vertical activity: left, time course; and right, total number; (C) speed; (D) freezing response. Statistics: Students t-test: G, genotype effect, G *p < 0.05, G **p < 0.01, G ***p < 0.001. ANOVA for comparisons between all the groups of mice followed by Bonferroni’s post-hoc test: *p < 0.05 and ***p < 0.01 vs. the NTg-group. Paired t-test, TT p < 0.01 vs. the same group on Day 1.