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Model explaining the regulation of the outcome of mitotic arrest by the Bcl-xL level and duration of mitotic arrest. After release from mitotic arrest cells divide or undergo mitotic slippage and rapidly restore anti-apoptotic proteins activity. Death after slippage area is shown in blue; death in mitosis is shown in red. Cells’ fates can be shifted from survival to death in mitosis or death after slippage by inhibiting Bcl-xL to a certain level.
