Table 3. Classification of the Association Between Influenza Vaccination and COVID-19 Outcomes Based on Receipt of PHE.
2019-2020 Cohort | ||
---|---|---|
Vaccinated | Unvaccinated | |
No. of individuals (%) | 1 229 487 (53.9) | 1 050 318 (46.1) |
SARS-CoV-2 infection | ||
No. of events (%) | 2584 (0.21) | 2745 (0.26) |
HR (95% CI) | 0.79 (0.75-0.83) | 1 [Reference] |
PHE 2018-2019, fully adjusted HR (95% CI) | ||
Yes | 0.62 (0.52-0.74) | |
No | 0.81 (0.76-0.87) | |
SARS-CoV-2–associated hospitalization | ||
No. of events (%) | 992 (0.08) | 980 (0.09) |
HR (95% CI) | 0.84 (0.77-0.92) | 1 [Reference] |
PHE 2018-2019, fully adjusted HR (95% CI) | ||
Yes | 0.64 (0.47-0.87) | |
No | 0.86 (0.77-0.97) | |
SARS-CoV-2–associated death | ||
No. of events (%) | 428 (0.03) | 441 (0.04) |
HR (95% CI) | 0.82 (0.72-0.93) | 1 [Reference] |
PHE 2018-2019, fully adjusted HR (95% CI) | ||
Yes | 0.46 (0.28-0.74) | |
No | 0.78 (0.66-0.92) | |
SARS-CoV-2–associated hospitalization or death | ||
No. of events (%) | 1104 (0.09) | 1093 (0.10) |
HR (95% CI) | 0.84 (0.77-0.91) | 1 [Reference] |
PHE 2018-2019, fully adjusted HR (95% CI) | ||
Yes | 0.66 (0.49-0.88) | |
No | 0.85 (0.76-0.95) |
Abbreviations: HR, hazard ratio; PHE, periodic health examination.