Table 5.

Improvement of the prognostic model by the addition of 12 inflammatory biomarkers to the base model, respectively.

	1 year AUC	P value	3 years AUC	P value	5 years AUC	P value
Model †	0.739 (0.682-0.795)		0.738 (0.690-0.787)		0.671 (0.600-0.742)
+ High IPS	0.803 (0.754-0.851)	<0.001	0.764 (0.717-0.810)	0.042	0.686 (0.613-0.759)	0.459
+ CRP≥13.2, mg/L	0.781 (0.729-0.833)	0.002	0.745 (0.697-0.792)	0.569	0.670 (59.61-74.39)	0.954
+ WBC≥7.10, 109/L	0.748 (0.693-0.803)	0.279	0.753 (0.706-0.800)	0.060	0.675 (0.602-0.747)	0.762
+ NEU≥5.40, 109/L	0.746 (0.690-0.802)	0.384	0.753 (0.705-0.800)	0.051	0.681 (0.608-0.753)	0.369
+ LYM<1.76, 109/L	0.742 (0.686-0.798)	0.148	0.739 (0.690-0.787)	0.813	0.672 (0.601-0.744)	0.683
+ Mon≥0.43, 109/L	0.750 (0.695-0.804)	0.238	0.751 (0.704-0.798)	0.154	0.672 (0.600-0.743)	0.969
+ RDW≥14.6, %	0.762 (0.709-0.816)	0.036	0.753 (0.706-0.801)	0.134	0.688 (0.618-0.759)	0.266
+ PLT<123, 109/L	0.741 (0.685-0.797)	0.688	0.748 (0.700-0.795)	0.053	0.674 (0.602-0.746)	0.689
+ NLR≥2.28	0.753 (0.698-0.808)	0.064	0.750 (0.702-0.797)	0.111	0.679 (0.607-0.751)	0.463
+ PLR≥99.66	0.751 (0.695-0.807)	0.010	0.745 (0.697-0.793)	<0.001	0.671 (0.600-0.742)	<0.001
+ LMR<3.97	0.750 (0.695-0.804)	0.143	0.741 (0.693-0.789)	0.680	0.662 (0.590-0.735)	0.454
+ SII≥310.73, 109/L	0.744 (0.688-0.799)	0.471	0.744 (0.696-0.792)	0.363	0.673 (0.601-0.745)	0.856
+ SIRI≥1.51, 109/L	0.752 (0.697-0.807)	0.080	0.741 (0.693-0.789)	0.703	0.664 (0.591-0.736)	0.509

†The model included age, sex, MAP, BUN and Log2 NT-proBNP.

IPS, inflammatory prognostic scoring; CRP, C-reactive protein; WBC, white blood cell; NEU, neutrophils; LYM, lymphocyte; Mon, monocyte; RDW, red blood cell distribution width; PLT, platelet; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet to lymphocyte ratio; LMR, lymphocyte-to-monocyte ratio; SII, systemic inflammation index; SIRI, systemic inflammatory response index.