. Author manuscript; available in PMC: 2022 Sep 29.

Published in final edited form as: Cell Calcium. 2018 Nov 27;77:20–28. doi: 10.1016/j.ceca.2018.11.008

Table 2:

Store-operated Ca2+ entry inhibitors.

Compound	IC₅₀	actions
2-APB and analogues	4.8–42 nM	Inhibits and activates	[104]
Imidazole SKF-96365	10 uM	Non-selective	[105]
Pyrazole	10–100 nM	Inhibits TRPM4 and Orai channels	[64, 106]
Synta-66	3uM	Direct to Orai	[107]
RO2959	400nM	Orai specific	[108]
CM2489, CM3457	n/a	n/a	calcimedica.com