Table 3. Forced Degradation Data of Clindamycin.
| Condition | % Degradation sample | Assay (% w/w) in degradation sample | Purity index | Single point threshold | Peak purity |
|---|---|---|---|---|---|
| Control sample (unstressed) | 1.15 | 98.8 | 1.000 | 0.999 | Passed |
| Acid degradation 1 M; HCl 120 min at @ 80 °C | 11.50 | 86.6 | 1.000 | 0.998 | Passed |
| Base degradation 1 M; NaOH 1 min @ 80 °C | 16.50 | 82.5 | 1.000 | 0.996 | Passed |
| Peroxide Stress 0.5% H2O2 | 11.30 | 85.5 | 1.0000 | 0.999 | Passed |
| Thermal Stress @ 80 °C 2 h | 13.50 | 85.6 | 1.000 | 0.999 | Passed |
| Photo Stress Fluorescent 1.2 M Lux and UV-200 W h–1 (Sample in ampule) direct exposure | 1.29 | 100.9 | 1.000 | 0.999 | Passed |