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. 2022 Sep 15;13:955841. doi: 10.3389/fimmu.2022.955841

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Copyright © 2022 Qin, Wang, Huang, Huang and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PRSS23 is associated with macrophage infiltration in GC. (A) Immune estimation analysis was conducted using two different methods. (B, C) The correlation between PRSS23 expression and immune infiltration was analyzed using TIMER and CIBERSORT methods. (D, E) The correlation between PRSS23 expression and macrophage infiltration was analyzed using TIMER and CIBERSORT methods. (F, G) Survival analysis using CIBERSORT or TIMER indicated that higher level of macrophage infiltration predicted poorer prognosis in GC.