TABLE 1.
Neuropsychological test scores at baseline and follow-up in subjects with NC at baseline (n = 37).
| Test | Baseline | Follow-up | P-value |
| Episodic memory | |||
| Prose recall | 13.3 (2.3) | 12.0 (3.1) | 0.021 a |
| ROCF-delayed recall | 23.4 (5.3) | 20.5 (7.0) | 0.066a |
| Executive functions | |||
| Bell Test | 34.4 (0.8) | 33.9 (1.1) | 0.042 a |
| Digit Cancellation Test | 53.5 (5.0) | 52.8 (6.4) | 0.599a |
| Digit Span Forwards | 5.7 (0.9) | 5.6 (1.0) | 0.827b |
| Digit Span Backwards | 4.4 (0.6) | 4.5 (0.8) | 0.299a |
| Trail-Making Test A | 28.8 (12.6) | 30.8 (13.8) | 0.561b |
| Trail-Making test B | 58.5 (32.6) | 74.8 (63.6) | 0.451b |
| Weigl’s Test | 12.2 (1.7) | 11.4 (2.7) | 0.122b |
| Cognitive Estimates-total | 10.3 (1.5) | 14.2 (3.3) | < 0.001 a |
| Cognitive Estimates-bizarre | 1.6 (0.8) | 3.5 (2.0) | < 0.001 a |
| Raven’s CPM | 32.9 (3.8) | 31.8 (5.4) | 0.421b |
| Letter fluency | 37.5 (7.6) | 33.9 (8.9) | 0.074a |
| Language | |||
| Category fluency | 18.6 (3.4) | 18.5 (4.5) | 0.777b |
| Picture naming | 75.0 (2.8) | 74.6 (4.3) | 0.937b |
| Token Test | 33.6 (1.1) | 33.0 (2.8) | 0.190a |
| Visuospatial skills | |||
| ROCF-copy | 34.9 (3.7) | 35.0 (2.7) | 0.899b |
| Copy of geometric figures | 13.7 (0.4) | 13.6 (0.8) | 0.793b |
| Ideomotor praxis | |||
| De Renzi’s test-right upper limb | 71.6 (0.8) | 71.3 (1.3) | 0.210b |
| De Renzi’s test-left upper limb | 71.0 (1.6) | 71.4 (1.0) | 0.142b |
Neuropsychological test scores reported as mean (standard deviation) and demographically-adjusted. Higher scores indicate better cognitive performance except for the Trail-Making and Cognitive Estimates tests for which the reverse applies.
aPaired t-test, bWilcoxon signed-rank test. Significant results are shown in bold typeface. NC, Normal Cognition; ROCF, Rey-Osterrieth Complex Figure; CPM, Colored Progressive Matrices.