TABLE 2.
Neuropsychological test scores at baseline and follow-up in subjects with MCI at baseline (n = 34).
| Test | Baseline | Follow-up | P-value |
| Episodic memory | |||
| Prose recall | 8.1 (4.7) | 7.8 (4.8) | 0.656a |
| ROCF-delayed recall | 14.3 (7.0) | 11.9 (9.7) | 0.027 b |
| Executive functions | |||
| Bell Test | 31.5 (2.7) | 32.1 (3.5) | 0.256a |
| Digit Cancellation Test | 50.1 (5.7) | 46.9 (8.7) | 0.017 b |
| Digit Span Forwards | 5.3 (0.9) | 4.9 (1.4) | 0.124b |
| Digit Span Backwards | 3.7 (0.7) | 3.6 (1.4) | 0.774b |
| Trail-Making Test A | 45.9 (23.8) | 53.2 (45.7) | 0.970b |
| Trail-Making test B | 200.6 (136.8) | 244.4 (169.1) | 0.008 b |
| Weigl’s Test | 9.4 (2.5) | 8.6 (2.8) | 0.088a |
| Cognitive Estimates-total | 13.2 (2.3) | 17.8 (3.4) | < 0.001 a |
| Cognitive Estimates-bizarre | 2.6 (1.2) | 5.1 (2.2) | < 0.001 a |
| Raven’s CPM | 27.5 (4.7) | 29.3 (16.1) | 0.428b |
| Letter fluency | 30.8 (8.5) | 27.8 (10.3) | 0.034 a |
| Language | |||
| Category fluency | 13.7 (3.1) | 13.5 (4.1) | 0.702a |
| Picture naming | 70.1 (5.2) | 67.1 (7.6) | 0.005 b |
| Token Test | 30.8 (2.0) | 30.3 (2.8) | 0.316a |
| Visuospatial skills | |||
| ROCF-copy | 32.1 (4.2) | 29.1 (5.9) | 0.006 b |
| Copy of geometric figures | 12.4 (1.4) | 12.0 (2.5) | 0.889b |
| Ideomotor praxis | |||
| De Renzi’s test-right upper limb | 70.5 (1.8) | 69.6 (3.6) | 0.136b |
| De Renzi’s test-left upper limb | 69.9 (1.9) | 69.5 (3.6) | 0.927b |
Neuropsychological test scores reported as mean (standard deviation) and demographically-adjusted. Higher scores indicate better cognitive performance except for the Trail-Making and Cognitive Estimates tests for which the reverse applies.
aPaired t-test, bWilcoxon signed-rank test. Significant results are shown in bold typeface. MCI, Mild Cognitive Impairment; ROCF, Rey-Osterrieth Complex Figure; CPM, Colored Progressive Matrices.