FIGURE 3.
Differential expression pattern of endoplasmic reticulum (ER) stress-related genes and survival in two bladder urothelial carcinoma (BLCA) subtypes. (A) Consistent cluster analysis was used to split the samples of patients with BLCA into two distinct clusters. (B) Curves of the cumulative distribution function with k values ranging from 2 to 6. (C) The expression patterns of genes associated with ER stress are shown using heat maps of the two BLCA clusters. (D) Differential expression of immune checkpoint-related genes in two clusters. (E, F) Overall survival of patients with BLCA (E) and disease-free survival of patients with BLCA (F) are shown using the Kaplan–Meier curves. (F) The expression of genes related to immune sites between the two clusters. *p < 0.05, **p < 0.01 and ***p < 0.001.
