Table 2. Evaluation of Tablet Mass, Tablets, and Dissolution on Formulations of 3CH2Cla.
| tablet | SLS | CS | flow
time |
Carr index | hardness |
friability | disintegrating time | drug
release |
|||
|---|---|---|---|---|---|---|---|---|---|---|---|
| code | [mg] | [mg] | [s] | SD | [%] | [kp] | SD | [%] | [min] | [%] | SD |
| TA | 4.00 | 32.00 | 7.63 | 0.06 | 21.00 | 7.36 | 0.77 | 0.31 | 2.53 | 59.41 | 0.95 |
| TB | 6.00 | 24.00 | 8.60 | 0.10 | 24.00 | 8.81 | 0.97 | 0.34 | 4.35 | 69.95 | 1.00 |
| TC | 8.00 | 16.00 | 9.33 | 0.06 | 26.00 | 9.76 | 0.59 | 0.38 | 5.65 | 85.04 | 1.05 |
| T opt. | 7.36 | 18.64 | 9.10 | 0.10 | 25.00 | 9.48 | 0.52 | 0.36 | 5.25 | 81.53 | 0.86 |
| P opt. | 7.36 | 18.64 | 9.07 | 25.33 | 9.44 | 0.37 | 5.22 | 80.00 | |||
a
The quality evaluation of tablets mass, tablets, and dissolution of each formula containing SLS [%] and CS [%]: TA (0.50:4.00), TB (0.75:3.00), TC (1.00:2.00), and T Opt. (0.92:2.33).