Table 4. Evaluation of the Release Kinetics of 3CH2Cla.
| formula code | parameter | first
order |
Higuchi |
Korsmeyer–Peppas |
Weibull |
kinetics model | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| average | SD | average | SD | average | SD | average | SD | |||
| TA | Rsqr_adj | 0.8545 | 0.02 | 0.9721 | 0.01 | 0.9779 | 0.01 | 0.9907 | 0.01 | Weibull |
| MSE_root | 8.4740 | 0.47 | 3.6791 | 0.57 | 3.2431 | 0.75 | 2.0408 | 0.80 | ||
| AIC | 37.2882 | 0.67 | 27.1910 | 1.89 | 26.2323 | 2.67 | 20.5635 | 4.56 | ||
| TB | Rsqr_adj | 0.9475 | 0.01 | 0.9966 | 0.00 | 0.9961 | 0.00 | 0.9917 | 0.00 | Higuchi |
| MSE_root | 5.7427 | 0.56 | 1.4227 | 0.47 | 1.5214 | 0.53 | 2.2621 | 0.46 | ||
| AIC | 32.5953 | 1.14 | 15.3644 | 4.53 | 16.8557 | 4.27 | 22.229 | 2.35 | ||
| TC | Rsqr_adj | 0.9578 | 0.01 | 0.9885 | 0.00 | 0.9949 | 0.00 | 0.9963 | 0.00 | Weibull |
| MSE_root | 6.3475 | 0.45 | 3.3264 | 0.47 | 2.221 | 0.13 | 1.8553 | 0.28 | ||
| AIC | 33.8125 | 0.87 | 26.0793 | 1.49 | 21.8932 | 0.65 | 19.9178 | 1.81 | ||
| T Opt. | Rsqr_adj | 0.9686 | 0.01 | 0.9926 | 0.00 | 0.9925 | 0.01 | 0.9979 | 0.00 | Weibull |
| MSE_root | 5.2892 | 0.42 | 2.5394 | 0.52 | 2.5334 | 0.39 | 1.2986 | 0.53 | ||
| AIC | 31.6188 | 0.97 | 22.6583 | 2.61 | 23.2554 | 0.57 | 14.8858 | 5.82 | ||
a
The release kinetics of 3CH2Cl from each tablet formula containing SLS [%] and CS [%]: TA (0.50:4.00), TB (0.75:3.00), TC (1.00:2.00), and T Opt. (0.92:2.33). The model selection was high Rsqr_adj, low mean square error root (MSE_root), and low Akaike Information Criterion (AIC).