Table 2.
Historical details of IPF cohort
| Variables N(%) or mean ± SD | Obese, BMI ≥30 kg/m2 (n = 49,35.5%) | Nonobese, BMI <30 kg/m2 (n = 89, 64.5%) | Total IPF cohort (n = 138) | P |
|---|---|---|---|---|
|
| ||||
| Age, y | 7327 ±9.12 | 77.97 ± 9.59 | 76.30 ± 9.66 | 0.002 |
| Male sex | 32 (65.3) | 51 (57.3) | 83 (60.1) | 0.246 |
| Family history of IPF | 4(8) | 7 (7.9) | 11(8) | 1.000 |
| Ever-smoking | 38 (77.5) | 61 (68.5) | 99(71.7) | 0.154 |
| Smoking pack-years | 33.71 ±33.49 | 34.12 * 24.21 | 33.96 ±28.12 | 0.472 |
| Comorbidities | ||||
| Hypertension | 44 (89.8) | 64(71.9) | 108(78.3) | 0.001 |
| Hyperlipidemia | 41 (83.7) | 61 (68.5) | 102(73.9) | 0.008 |
| GERD | 35 (71.4) | 62 ((>9.7) | 97 (70.3) | 0.876 |
| CAD | 31 (63.3) | 47 (52.8) | 78 (56.5) | 0.151 |
| COPD | 21 (42.9) | 36 (40.4) | 57(41.3) | 0.667 |
| CHF | 21 (42.9) | 32 (36) | 53 (38.4) | 0.311 |
| Sleep apnea | 23 (47) | 23 (25.8) | 46 (33.3) | 0.002 |
| Diabetes mcllitus | 23 (47) | 23 (25.8) | 46 (33.3) | 0.002 |
| PH | 19(38.8) | 31 (34.8) | 50 (36.2) | 0.462 |
| Atrial arrhythmia | 15(30.6) | 33 (37.1) | 48 (34.7) | 0.294 |
| Anxiety/mood disorders | 15(30.6) | 28(31.5) | 43 (31.2) | 0.879 |
| Chronic pain | 14(28.6) | 14(15.7) | 28 (20.3) | 0.027 |
| Hypothyroidism | 13(26.5) | 32 (36) | 45 (32.6) | 0.126 |
| Anemia | 12(24.5) | 30 (33.7) | 42 (30.4) | 0.119 |
| DVT | 10(20.4) | 7 (7.9) | 17(12.3) | 0.014 |
| CVA | 6(12.2) | 19(21.3) | 25(18.1) | 0.086 |
| PVD | 5(10.2) | 10(11.2) | 15(10.9) | 0.817 |
| Aortic aneurysm | 2(4) | 13(14.6) | 15(10.9) | 0.008 |
| Lung cancer | 2(4) | 5 (5.6) | 7(5.1) | 0.516 |
Italicized/bold P values refers to significant P values.
CAD, coronary artery disease; CHF, congestive heart failure; CKD, chronic kidney disease; COPD; chronic obstructive pulmonary disease; CVA, cerebrovascular accident; DVT, deep vein thrombosis; GERD, gastroesophageal reflux disease; IPF, idiopathic pulmonary fibrosis; PH, pulmonary hypertension; PVD, peripheral vascular disease; SD, standani deviation.