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. 2022 Sep 15;16:915995. doi: 10.3389/fnhum.2022.915995

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Copyright © 2022 Zhang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Changed structure and function in motor cortex in HA population. (A) The decreased gray matter volume (Zhang et al., 2010) (a) and cerebrovascular reactivity (Yan et al., 2011b) (b) in the descendants of Han population who have immigrated to HA for several generations; (B) the decreased cortical thickness in HA Tibetan natives (Wei et al., 2017); (C) the decreased white matter fiber volume projecting from motor cortex in Everest climbers (Di Paola et al., 2008). (D) the decreased the gray matter volume (Zhang et al., 2013b) (a) and increased regional homogeneity in soldiers who had garrisoned the frontiers at HA for 2 years (Chen et al., 2016a) (b); (E) the increased cortical thickness in sea-level college students who had a 30-day teaching at HA (Fan et al., 2016). The arrow indicates the motor cortex.