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. 2022 Sep 15;12:971288. doi: 10.3389/fonc.2022.971288

Figure 1.

Figure 1

Classification of Breast Cancer (A) Breast showing the different tissue types consisting of duct, lobe, lobules, nipples, and fatty tissue. (B) Cross-sectional view of mammary duct, consisting of basal cells and luminal cells. Breast cancer arising from the luminal or basal cells can be further characterized based on the expression of different hormone receptors. (C) Based on the expression of ER, PR, HER2, and proliferation status as assessed by Ki67, different molecular subtypes of breast cancer have been identified that have distinct prognostic features and response to therapies (3).