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. 2022 Sep 15;13:1007326. doi: 10.3389/fimmu.2022.1007326

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Copyright © 2022 Chen, Chen, Dai, Ma, Chen, Bian and Sun

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Molecular typing based on DPT, RUNX1T1, PTPRN, LSAMP, FDCSP and COL6A6. (A) Among all the characteristic genes, DPT, RUNX1T1, PTPRN, LSAMP, FDCSP and COL6A6 were identified for their prognosis correlation (P < 0.05); (B) ConsensusClusterPlus package was used for molecular typing in the patients of TCGA database; (C) Dividing patients into two subtypes provides the best differentiation; (D) KM survival curve of patients in Cluster1 and Cluster2; (E, F) The patients in Cluster2 had a higher TIDE score than Cluster1; (G–L) The prediction ability of DPT, RUNX1T1, PTPRN, LSAMP, FDCSP and COL6A6 on patients immunotherapy response.