Figure 4.
Photomicrographs of the cryosections of the skin of a dog with atopic dermatitis (AD) showing IBA1 immunoreactive cells (macrophages and dendritic cells) expressing transient receptor potential vanilloid 1 (TRPV1) (a–d) and ankyrin 1 (TRPA1) immunoreactivity (IR) (e–h). The white arrows indicate the Dapi-labeled nuclei of IBA1 positive cells co-expressing TRPV1-IR (c) and TRPA1-IR (g). The open arrow indicates one IBA1 negative cell which expressed TRPV1- (c) and TRPA1-IR (g). Bar: 50 μm.