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. 2022 Sep 15;13(9):696–716. doi: 10.4239/wjd.v13.i9.696

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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Altered cellular factors and biochemical mediators involved in the development of diabetic wound. Nrf2: Nuclear factor erythroid factor 2-related factor 2; ROS: Reactive oxygen species; EPC: Endothelial progenitor cell; MMP: Matrix metalloproteinase; TIMP: Tissue inhibitor of metalloproteinase; ECM: Extracellular matrix.