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. 2022 Sep 15;13:989417. doi: 10.3389/fphar.2022.989417

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Copyright © 2022 Pant, Miranda-Hernandez, Rush, Warner and Eisen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Downregulation of biofilm-related genes by savirin after 8 h of culture (* = downregulated > 2-fold). The reference gene used was fema and the experiment was performed in triplicate (N = 3). To determine the effect of savirin (10 ug/ml) treatment on the S. aureus biofilm-related genes, comparative C_t (ΔΔC_t) method was used and the results were expressed as mean fold changes ± standard deviation (SD) in comparison with savirin diluent (0.02% Dimethyl Sulphoxide) treated control. The error bars indicate SD.