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. 2022 Sep 29;17(9):e0273789. doi: 10.1371/journal.pone.0273789

Table 2. Composite disease activity indices formulas.

Composite Disease Activity Index Formula
DAS28-ESR 0,56 x √TJC28 + 0,28 x √SJC28 + 0,70 x lnESR + 0,014 x GH
DAS28-CRP 0,56 x √TJC28 + 0,28 x √SJC28 + 0,36 x ln(CRP+1) + 0,014 x GH + 0,96
SDAI SJC + TJC+ PtGA + PhGA + CRP (mg/dL)
CDAI SJC + TJC+ PtGA + PhGA

DAS28-CRP: Disease Activity Score 28- C reactive protein; DAS28-ESR: Disease Activity Score 28 -erythrocyte sedimentation rate; SDAI: Simplified Activity Index; CDAI: Clinical Activity Index; SJC: swollen joint count; TJC: tender joint count; GH: global health assessment (0–100 mm); PtGA: patient global assessment (0–10 cm); PhGA: physician global assessment (0–10 cm; ESR: erythrocyte sedimentation rate; CRP: C reactive protein.