Skip to main content
. 2022 Sep 29;17(9):e0274553. doi: 10.1371/journal.pone.0274553

Table 4. Characteristic times for the waning antibodies.

Group Antibody T50 in days (IQR) T90 in days (IQR) Estimated % relative loss between T2 and T3
1 (n = 74) RBD 50 (42–58) 168 (140–193) 87% (82–91)
S1 53 (45–68) 177 (149–227) 86% (77–90)
S2 86 (59–123) 287 (197–309) 69% (56–81)
2 (n = 9) RBD 55 (48–61) 182 (160–203) 84% (76–86)
S1 49 (46–65) 164 (153–214) 84% (71–89)
S2 37 (37–51) 122 (121–168) 92% (71–94)
3 (n = 6)  RBD  84 (62–102) 278 (205–340) 71% (64%– 82%)
S1  82 (78–91) 272 (258–302) 72% (68%– 74%)
S2  122 (94–155) 404 (312–514) 58% (49%– 67%)

The half-life T50 (T90) equals the number of days at which there is 50% (10%) left from the estimated DF50 at time zero assuming an exponential decay. The estimated % relative loss is calculated as [DF50(T2)—DF50(T3)) / DF50(T2). We compared specific antibodies between groups 1 and 2 using a Wilcoxon rank sum test: RBD, p = 0.330; S1, p = 0.855: S2, p = 0.001.