Table 1. Correlation between circRNA expression changes and PASI during 84 days of secukinumab treatment.
| circRNA | R | R squared | p-value |
|---|---|---|---|
| circPTPRA | - 0.7681 | 0.5900 | <0.0001 |
| ciRS-7 | - 0.7284 | 0.5305 | <0.0001 |
| circSCMH1 | - 0.7068 | 0.4995 | <0.0001 |
| circTULP4 | - 0.6769 | 0.4582 | <0.0001 |
| circSLC8A1 | - 0.6722 | 0.4518 | <0.0001 |
| circVCAN | - 0.6710 | 0.4502 | <0.0001 |
| circZC3H6 | - 0.6474 | 0.4191 | <0.0001 |
| circCCDC9 | - 0.6280 | 0.3944 | <0.0001 |
| circPARD3 | - 0.5612 | 0.3149 | <0.0001 |
| circZNF91 | - 0.4877 | 0.2379 | <0.0001 |
Only significantly deregulated circRNAs with a fold change higher than 2 in lesional relative to non-lesional skin before treatment and normalization of expression upon treatment at day 84 are shown.