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. 2022 Sep 29;17(9):e0275296. doi: 10.1371/journal.pone.0275296

Table 1. Clinical characteristics of patients.

RCM 1 RCM 2 RCM 3
Sex Male Male Female
Age at diagnosis 2 years 6 years 8 months
Age at sampling 3 years 11 years 2 years
Event at sampling LVAD LVAD HTx
LVEDP 24 mmHg 24 mmHg 25 mmHg
Medications at sampling Dobutamine Milrinone LVAD
Milrinone Diuretics Dobutamine
Diuretics ACE inhibitor Milrinone
Beta-blocker Amiodarone Diuretics
Aspirin Aspirin Warfarin
BNP at sampling 568.8 pg/mL 2577.5 pg/mL 949.7 pg/mL
Pathogenic Gene variants TNNI3 (R170W) TNNI3 (R192H) Not detected

LVEDP, left ventricular end diastolic pressure; BNP, brain natriuretic peptide; LVAD, left ventricular assist device; HTx, heart transplantation; ACE, angiotensin-converting enzyme.