Table 2.
Frequency of Chest Radiograph Features by Standard Clinical Case Definitions in Children Investigated for Intrathoracic Tuberculosis
| Overall, n (%) | Confirmed TB, n (%) | Unconfirmed TB, n (%) | Unlikely TB, n (%) | P valueb | |
|---|---|---|---|---|---|
| Number of CR readsa | 1082 | 236 | 334 | 512 | |
| Any abnormality | 884 (82) | 225 (95) | 286 (86) | 373 (73) | <.05 |
| Alveolar opacification | 422 (39) | 118 (50) | 123 (37) | 181 (35) | <.05 |
| Bronchopneumonia | 144 (13) | 35 (15) | 51 (15) | 58 (11) | .19 |
| Collapse | 79 (7) | 15 (6) | 21 (6) | 43 (8) | .38 |
| Perihilar infiltrates | 254 (23) | 40 (17) | 82 (25) | 132 (26) | <.05 |
| Interstitial infiltrates | 96 (9) | 8 (3) | 42 (13) | 46 (9) | <.05 |
| Enlarged perihilar lymph nodesc | 186 (17) | 100 (42) | 61 (18) | 25 (5) | <.05 |
| Enlarged paratracheal lymph nodesc | 91 (8) | 54 (23) | 27 (8) | 10 (2) | <.05 |
| Tracheal deviation/compression | 27 (2) | 22 (9) | 3 (<1) | 2 (<1) | <.05 |
| Bronchial deviation/compression | 100 (9) | 69 (29) | 22 (7) | 9 (2) | <.05 |
| Miliary infiltrates | 23 (2) | 15 (6) | 7 (2) | 1 (<1) | <.05 |
| Ghon focus | 18 (2) | 9 (4) | 6 (2) | 3 (<1) | <.05 |
| Cavities | 61 (6) | 32 (14) | 17 (5) | 12 (2) | <.05 |
| Expansile pneumonia | 16 (1) | 12 (5) | 1 (<1) | 3 (<1) | <.05 |
| Pleural effusion | 57 (5) | 21 (9) | 14 (4) | 22 (4) | <.05 |
Abbreviations: CR, chest radiograph; TB, tuberculosis.
Each CR generated 2 single independent CR reads (each read was based on assessment of anteroposterior or posteroanterior film with/without lateral film).
P values calculated using Fisher exact test to compare the groups confirmed and unlikely TB.
Perihilar or paratracheal lymph nodes classified as “uncertain” were excluded.