Fig. 4.

Visual inspection of ¹¹C-CPPC total distribution volume (V_T) values across the human brain reveals thalamus as one of the regions of highest binding, and relatively lower binding in cerebellar cortex. Parametric V_T images and MRI images in three views are shown from a representative healthy participant. V_T was estimated from 90-min data using Logan graphical analysis with the metabolite-corrected arterial input function. V_T is in units of mL cm⁻³. The V_T image was filtered with a 2 mm FWHM 3D Gaussian to reduce noise