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. 2022 Sep 29;12:16285. doi: 10.1038/s41598-022-20858-5

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Correlation of tumor mutation burden (TMB) with survival outcomes. (A) Waterfall chart of somatic mutations of necroptosis-related genes. The bar plot above showed the tumor mutation burden. The right number represented mutation frequency individually. (C) High TMB group was associated with higher survival probability. (D) The H-TMB + low risk group had the highest 2-year survival probability trend of the four subgroups.