Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Sep 16;9:942342. doi: 10.3389/fcvm.2022.942342

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Griepke, Grupe, Lindholt, Fuglsang, Steffensen, Beck, Larsen, Bang-Møller, Overgaard, Rasmussen, Lambertsen and Stubbe.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

TNF receptor protein levels and receptor localization in murine and human abdominal aortic tissue. (A) Aneurysmal protein levels of TNFR1 and TNFR2 from PPE- induced aneurysm in mice treated with vehicle (saline), ETN (20 mg/kg), or XPro1595 (20 mg/kg) (n = 3–5). Data are shown as mean SEM. A non-significant trend was detected in TNFR1 levels by one-way ANOVA using Bonferroni test for multiple comparisons. (B) Representative distribution of TNFR1 and TNFR2 in the PPE-induced AAA wall after treatment with saline, ETN, or XPro1595 for 14 days (n = 3–5). (C) TNFR1 distribution in unchallenged thoracic murine aorta. (D) Distribution of TNFR1 in human AAA specimens (n = 2) and human ascending aortas (n = 2). Black arrowheads indicate positive stained cells. M, media; Ad, adventitia.