TABLE 5.

Network measures between POE and opioid naïve infants based on fractional anisotropy (FA).

Network Measure	POE vs. Cont. (SE)	t-stat	p-value	p-corr
Betweenness centrality
Cuneus – R	93.3 (27.95)	3.34	0.003	0.086
Hippocampus – L	−194.23 (81.31)	−2.39	0.025	0.273
Hippocampus – R	−118.81 (42.54)	−2.79	0.010	0.19
Lateral OFC – L	−1.58 (0.74)	−2.13	0.043	0.369
Medial OFC – R	36.38 (15.59)	2.33	0.028	0.273
Inferior Parietal – L	65.37 (18.97)	3.45	0.002	0.086
Rectus – L	205.45 (75.78)	2.71	0.012	0.191
Rectus – R	168.55 (47.09)	3.58	0.002	0.086
Supp. Motor – R	−70.59 (29.11)	−2.43	0.023	0.273
Supramarginal – ‘R	47.63 (20.51)	2.32	0.029	0.273
Thalamus – R	−153.34 (54.79)	−2.80	0.010	0.19
Cluster coefficient
Middle Occipital – L	−0.033 (0.014)	−2.28	0.032	0.925
Rectus – R	−0.042 (0.019)	−2.22	0.036	0.925
Supp. Motor – L	−0.027 (0.013)	−2.13	0.044	0.925
Thalamus – L	−0.04 (0.018)	−2.24	0.034	0.925
Local efficiency
Middle Occipital – R	−0.048 (0.022)	−2.16	0.041	0.853
Paracentral Lobule – R	−0.052 (0.02)	−2.54	0.018	0.853
Pagerank centrality
Middle Occipital – R	−0.001 (0.0006)	−2.08	0.049	0.761
Medial OFC – L	0.001 (0.0006)	2.22	0.036	0.761
Precuneus – L	−0.002 (0.0007)	−2.47	0.021	0.761
Supp. Motor – R	−0.002 (0.0006)	−3.15	0.004	0.408
Inferior Temporal – L	0.001 (0.0005)	2.12	0.044	0.761