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The diagram of total study (A) Neoadjuvant treatment; (B) Study population.The diagram of total study (A) Neoadjuvant treatment; (B) Study population. pNCT prolonged neoadjuvant chemotherapy; TNT, total neoadjuvant therapy; BMI, Body mass index; CRM, circumference resection margin; EMVI, extramural vascular invasion; TME, total mesorectal excision.
