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. 2022 Sep 16;12:953790. doi: 10.3389/fonc.2022.953790

Table 1.

Baseline clinical characteristics of patients before and after propensity scoring matching.

Characteristic Before matching After matching
pNCTN=131 TNTn=98 P pNCTN=92 TNTN=92 P
Sex (%) Male 103 (78.6) 76 (77.6) 0.974 74 (80.4) 70 (76.1) 0.592
Female 28 (21.4) 22 (22.4) 18 (19.6) 22 (23.9)
Age, years (SD) 60.91 (9.23) 60.90 (8.68) 0.993 61.23 (8.64) 60.60 (8.61) 0.621
BMI (SD) 22.93 (3.32) 22.92 (2.53) 0.993 22.87 (3.08) 22.93 (2.56) 0.871
Distance from anal verge, cm (SD) 6.34 (2.32) 6.02 (1.99) 0.282 5.95 (1.97) 6.01 (2.01) 0.853
Pretreatment CEA level, ng/ml (SD) 7.31 (13.69) 4.52 (7.76) 0.071 4.42 (5.63) 3.61 (4.76) 0.293
cT (%) cT1 0 (0.0) 2 (2.0) 0.208 0 (0.0) 2 (2.2) 0.275
cT2 4 (3.1) 4 (4.1) 3 (3.3) 3 (3.3)
cT3 65 (49.6) 39 (39.8) 48 (52.2) 38 (41.3)
cT4 62 (47.3) 53 (54.1) 41 (44.6) 49 (53.3)
cN (%) cN0 10 (7.6) 4 (4.1) 0.516 6 (6.5) 4 (4.3) 0.718
cN1 49 (37.4) 40 (40.8) 34 (37.0) 38 (41.3)
cN2 72 (55.0) 54 (55.1) 52 (56.5) 50 (54.3)
CRM (%) Negative 52 (39.7) 32 (32.7) 0.339 29 (31.5) 31 (33.7) 0.875
Positive 79 (60.3) 66 (67.3) 63 (68.5) 61 (66.3)
EMVI (%) Negative 53 (40.5) 37 (37.8) 0.781 35 (38.0) 35 (38.0) 1
Positive 78 (59.5) 61 (62.2) 57 (62.0) 57 (62.0)
Median Follow-up Time months (min-max) 34.5 (9-61) 36 (5-64)

pNCT, prolonged neoadjuvant chemotherapy; TNT, total neoadjuvant therapy; BMI, Body mass index; CRM, circumference resection margin; EMVI, extramural vascular invasion.