Table 3.

Comparison of toxicity and adverse event.

Adverse Event	pNCTn=92	TNTn=92	P
Chemotherapy-related adverse event (%)
Death	0	0
Leukopenia (Grade 3, 4†)	4 (4.35)	3 (3.26)	0.702
Anemia (Grade 3, 4†)	0	1 (1.09)	0.319
Thrombocytopenia (Grade 3, 4†)	1 (1.09)	0	0.319
Diarrhea (Grade 3, 4†)	2 (2.18)	1 (1.09)	0.563
Postoperative complications (%)
Death	0	0
Bleeding (Grade 3, 4#)	1 (1.09)	2 (2.18)	0.563
Anastomosis leakage (Grade B, C*)	5 (5.43)	7 (7.61)	0.234
Wound infection (Grade 3, 4#)	0	1 (1.09)	0.319

^†Common Terminology Criteria for Adverse Events (CTCAE).

^#Clavien-Dindo classification.

^*Classification of International Study Group of Rectal Cancer (ISREC).