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. 2022 Sep 16;13:986802. doi: 10.3389/fphar.2022.986802

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Copyright © 2022 Ahsan, Mushtaq, Saleem, Malik, Sarfaraz, Shahzad, Uhlin and Ahmad.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of the oral administration of the extract from S. lappa in mice infected with the AB5075 or AB-4 strains of A. baumannii (A) Total neutrophil counts in the whole blood of mice withdrawn through heart puncture after 20 h of infection. Number of viable bacterial counts shown as colony forming unit (CFU) count in liver (B), lungs (C) and spleen (D) of the mice sacrificed after 20 h of intraperitoneal infection consisting of 10⁷ cells suspended in phosphate buffer saline. Bars show mean ± standard deviation of the individual values obtained from six mice in each group. Statistical significance is indicated by *p < 0.05 and **p < 0.01 and ***p < 0.001 using non-parametric t test.