Table 1. Baseline Characteristics.
| Characteristic | Total (n = 1241) | Event | P | |||
|---|---|---|---|---|---|---|
| Yes (n = 131) | No (n = 1110) | |||||
| Age, years | 60.2 ± 10.4 | 63.3 ± 11.4 | 59.9 ± 10.2 | 0.001 | ||
| Male | 671 (54.1) | 79 (60.3) | 592 (53.3) | 0.130 | ||
| Body mass index, kg/m2 | 26.2 ± 3.6 | 26.2 ± 3.8 | 26.2 ± 3.6 | 0.779 | ||
| Cardiac risk factors | ||||||
| Hypertension | 824 (66.4) | 92 (70.2) | 732 (65.9) | 0.326 | ||
| Hyperlipidemia | 665 (53.6) | 87 (66.4) | 578 (52.1) | 0.002 | ||
| Smoking | 340 (27.4) | 45 (34.4) | 295 (26.6) | 0.059 | ||
| Family history of CAD | 295 (23.8) | 28 (21.4) | 267 (24.1) | 0.496 | ||
| CCTA findings | ||||||
| CAD-RADS | ||||||
| 0 | 190 (15.3) | 5 (3.8) | 185(16.7) | < 0.001 | ||
| 1 | 121 (9.8) | 4 (3.1) | 117 (10.5) | 0.006 | ||
| 2 | 502 (40.5) | 41 (31.3) | 461 (41.5) | 0.024 | ||
| 3 | 215 (17.3) | 27 (20.6) | 188 (16.9) | 0.293 | ||
| 4 | 189 (15.2) | 49 (37.4) | 140 (12.6) | < 0.001 | ||
| 5 | 24 (1.9) | 5 (3.8) | 19 (1.7) | 0.098 | ||
| Leiden risk score | 5.1 (1.2–11.1) | 10.6 (5.1–14.6) | 4.6 (1.2–10.6) | < 0.001 | ||
| Confirm score | 13.4 (8.4–18.0) | 16.5 (12.4–22.4) | 12.9 (7.5–17.3) | < 0.001 | ||
| High-risk plaque | 66 (5.3) | 23 (17.6) | 43 (3.9) | < 0.001 | ||
| Medication | ||||||
| Anti-platelet | 480 (38.7) | 45 (34.4) | 435 (39.2) | 0.280 | ||
| Beta blocker | 408 (32.9) | 40 (30.5) | 368 (33.2) | 0.550 | ||
| ACEI/ARB | 287 (23.1) | 35 (26.7) | 252 (22.7) | 0.300 | ||
| Statin | 482 (38.8) | 64 (48.9) | 418 (37.7) | 0.013 | ||
| Calcium channel blocker | 262 (21.1) | 32 (24.4) | 230 (20.7) | 0.330 | ||
| Diabetic treatment | ||||||
| Diet only | 248 (20.0) | 22 (16.8) | 226 (20.4) | 0.330 | ||
| Oral hypoglycemic agent | 901 (72.6) | 95 (72.5) | 806 (72.6) | 0.980 | ||
| Insulin | 300 (24.2) | 34 (26.0) | 266 (24.0) | 0.610 | ||
Values are mean ± standard deviation, number of patients (%), or median (interquartile range). ACEI = angiotensin-converting enzyme inhibitors, ARB = angiotension II receptor blockers, CAD = coronary artery disease, CCTA = coronary computed tomography angiography, RADS = Reporting and Data System