Table 4. Comparison of Normative Percentiles of Regional Brain Volume Derived from NQ and DB in the Total Study Population.
| Lt. Hemisphere | Rt. Hemisphere | ||||
|---|---|---|---|---|---|
| NQ | DB | NQ | DB | ||
| Cortical GM | |||||
| SMC | 74.04 ± 26.54 | 23.40 ± 28.40 | 76.99 ± 24.62 | 27.85 ± 30.84 | |
| ADNI | 40.86 ± 30.00 | 27.74 ± 34.81 | 40.04 ± 30.47 | 27.18 ± 34.87 | |
| Caudate | |||||
| SMC | 49.32 ± 31.89 | 37.84 ± 39.73 | 50.85 ± 30.88 | 57.62 ± 34.11 | |
| ADNI | 47.71 ± 31.16 | 31.00 ± 33.42 | 47.76 ± 32.60 | 42.22 ± 36.58 | |
| Putamen | |||||
| SMC | 50.43 ± 31.21 | 65.98 ± 33.43 | 55.77 ± 30.47 | 68.16 ± 31.59 | |
| ADNI | 39.32 ± 29.93 | 45.02 ± 34.09 | 43.80 ± 30.43 | 39.67 ± 32.69 | |
| Pallidum | |||||
| SMC | 46.59 ± 29.53 | 65.44 ± 32.04 | 45.57 ± 28.47 | 74.47 ± 27.41 | |
| ADNI | 29.53 ± 24.12 | 57.78 ± 35.25 | 31.83 ± 24.57 | 49.68 ± 32.81 | |
| Thalamus | |||||
| SMC | 53.90 ± 28.17 | 24.81 ± 31.21 | 63.19 ± 26.32 | 43.50 ± 33.39 | |
| ADNI | 63.76 ± 24.11 | 20.15 ± 28.60 | 57.62 ± 26.72 | 23.85 ± 28.32 | |
| Amygdala | |||||
| SMC | 64.32 ± 32.31 | 50.03 ± 36.92 | 68.01 ± 31.14 | 54.91 ± 35.40 | |
| ADNI | 34.96 ± 32.86 | 24.82 ± 35.11 | 35.76 ± 31.20 | 24.74 ± 33.39 | |
| Hippocampus | |||||
| SMC | 65.30 ± 34.43 | 50.43 ± 38.96 | 69.19 ± 33.00 | 56.25 ± 37.57 | |
| ADNI | 87.98 ± 20.27 | 74.91 ± 30.73 | 91.77 ± 13.27 | 76.79 ± 26.56 | |
| Cerebellar GM | |||||
| SMC | 57.01 ± 27.52 | 40.07 ± 32.94 | 57.93 ± 27.01 | 35.64 ± 32.87 | |
| ADNI | 47.90 ± 30.35 | 54.00 ± 36.84 | 46.00 ± 30.45 | 48.75 ± 36.30 | |
| Cerebellar WM | |||||
| SMC | 73.56 ± 23.27 | 30.23 ± 31.29 | 76.37 ± 22.61 | 29.18 ± 30.32 | |
| ADNI | 59.93 ± 27.43 | 31.32 ± 32.21 | 61.44 ± 28.27 | 32.12 ± 32.36 | |
| Cerebral WM | |||||
| SMC | 48.03 ± 26.49 | 40.07 ± 32.94 | 51.45 ± 26.64 | 52.11 ± 32.82 | |
| ADNI | 38.54 ± 27.53 | 49.93 ± 34.47 | 39.94 ± 27.27 | 48.76 ± 34.82 | |
| Total cortical GM | |||||
| SMC | 75.64 ± 25.34 | 25.18 ± 29.74 | |||
| ADNI | 40.12 ± 30.22 | 27.07 ± 34.72 | |||
| Total cerebral WM | |||||
| SMC | 49.77 ± 26.22 | 51.08 ± 33.44 | |||
| ADNI | 39.18 ± 27.33 | 49.25 ± 34.18 | |||
| TICV | |||||
| SMC | 26.60 ± 23.84 | 36.41 ± 34.91 | |||
| ADNI | 45.92 ± 27.73 | 74.62 ± 34.52 | |||
Data are mean ± standard deviation. AD = Alzheimer’s disease, ADNI = Alzheimer’s Disease Neuroimaging Initiative, DB = DeepBrain, FS = FreeSurfer, GM = gray matter, MCI = mild cognitive impairment, NL = normal elderly participants, NQ = NeuroQuant, SMC = single medical center, TICV = total intracranial volume, WM = white matter