Fig. 3.

Identification of tumour-associated antigens.

(A) Euler diagram. Circle sizes represent the absolute number of source proteins identified in all non-HCC and HCC tissues. Best covered KEGG pathways by HCC-exclusive proteins are indicated. (B) STRING protein–protein interaction network of HCC-exclusive source proteins with at least 3 protein interactions and their connecting nodes. The width of an edge connecting 2 nodes represents the interaction confidence (≥0.7). Nodes annotated to 3 main GO molecular functions are color-coded as indicated. (C) Euler diagram. Circle sizes represent the number of described HCC-associated tumour-associated antigens in each tissue. GO, Gene Ontology; HCC, hepatocellular carcinoma; KEGG, Kyoto Encyclopedia of Genes and Genomes.