The recommended follow-up time points are indicated by black rectangles; each time point with expected 5% local and distant events is indicated by orange and blue arrows, respectively. For all 5 groups, when more events occurred, more follow-up visits were recommended. HPC refers to hypopharynx cancer; HPV, human papillomavirus; HPV− OPC, human papillomavirus-negative oropharynx cancer; HPV+ OPC, human papillomavirus-positive oropharynx cancer; LC, larynx cancer; and NPC, squamous cell carcinoma of the nasopharynx.