Table 2. Commonly Used Solubility Enhancing Fusion Tags.
| tags | protein | source organisms | MW (kDa) | ref |
|---|---|---|---|---|
| Mal-bp | Maltose-binding protein | Escherichia coli | 43 | (416, 417) |
| GST | Glutathione S-transferase | Schistosoma japonicum | 26 | (418) |
| TRX | Thioredoxin | Escherichia coli | 12 | (418) |
| SlyD | FKBP-type peptidyl–prolyl cis–trans isomerase SlyD | Escherichia coli | 196 | (419) |
| DsbA | Disulfide-bond A oxidoreductase | Escherichia coli | 21 | (423) |
| NusA | N-Utilization substance | Escherichia coli | 55 | (91) |
| T7PK | Phage T7 protein kinase | Bacteriophage T7 | 17 | (414) |
| Skp | Seventeen kilodalton protein | Escherichia coli | 17 | (428) |
| HaloTag7 | Modified haloalkane dehalogenase | Escherichia coli | 34 | (420) |
| CBDengD | CBD of noncellulosomal cellulase EngD | Clostridium cellulovorans | 20 | (426) |
| SEP(C9R) | GFP-based superecliptic pHluorin | Aequorea victoria | 1.6 | (424, 425) |
| MOCR | monomeric Ocr | Escherichia coli | 16 | (455) |